From 2007 to 2008 she starred as Pizza Girl on the television series October Road. One of her best known roles has come starring as Cassandra Cillian on the TV series The Librarians beginning in 2014. Booth has also appeared in several films including Detroit Rock City, Wrong Turn, Dawn of the Dead, Cry Wolf, Kick-Ass 2, and more. She has also appeared in episodes of the TV series including The Twilight Zone, CSI: NY, Ghost Whisperer, Cold Case, NCIS, and more.