Jamal Mixon made his debut starring in the movie The Nutty Professor in 1996. He had a recurring role as Alan in the television series The Parkers in 2002. Mixon has also starred in the movies How to Be a Player, Bulworth, Beverly Hood, Nutty Professor II: The Klumps, The Cookout, Gridiron Gang, Paul Blart: Mall Cop, Steppin: The Movie, and White T. He has also appeared in episodes of the TV series Malcolm & Eddie, Moesha, The Good News, George Lopez, and The Big Leaf.