Zanardi made the transition to handcycling and he won his first senior international medal in 2011 winning a silver at the UCI World Road Para-Cycling Championships. He won gold medals at the London Paralympics in 2012. The same year he was included by International Paralympic Committee into the London 2012: Top 12 performances list. The Alex Zanardi Edition Acura NSX was introduced in 1999 to the U.S. market. He has won the Italian Superturismo, CART FedEx Championship Series, and European F3 Cup.